 | Figure 2
Nature Genetics
30, 233 - 237 (2002)
Published online: 14 January 2002; | doi:10.1038/ng826
Identification of a variant associated with adult-type hypolactasiaNabil Sabri Enattah, Timo Sahi, Erkki Savilahti, Joseph D. Terwilliger, Leena Peltonen
& Irma Järvelä | | | | Figure 2. Physical map of adult lactase non-persistence locus.
BAC clones are shown above the horizontal line. The three genes LCT, MCM6 and DARS are shown by thick black arrows indicating 5' 3' direction. The positions of ten polymorphic microsatellite markers used for fine mapping of the locus are given. The backslashes in the horizontal line denote gaps in the contig sequence. The position of marker D2S2169 was confirmed by bridging the gap with PAC 106O20 isolated from the PAC library. The organization of MCM6 is shown below, including the position of the lactase persistence−associated variants in introns 9 and 13, located 13.9 kb and 22 kb 5' of the first ATG of LCT.
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