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News and Views
Nature Genetics  29, 109 - 111 (2001)
doi:10.1038/ng1001-109

Islands of linkage disequilibrium

David B. Goldstein

Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK. d.goldstein@ucl.ac.uk

A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene mapping. New data suggest that linkage disequilibrium is highly structured into discrete blocks of sequence separated by hot spots of recombination.

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See also: Letter by Jeffreys et al.
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