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Brief Communication
Nature Genetics  29, 20 - 21 (2001)
Published online: 20 August 2001; | doi:10.1038/ng711

Human mtDNA and Y-chromosome variation is correlated with matrilocal versus patrilocal residence

Hiroki Oota1, 2, Wannapa Settheetham-Ishida3, Danai Tiwawech4, Takafumi Ishida5 & Mark Stoneking1

1  Max Planck Institute for Evolutionary Anthropology, Inselstrasse 22, D-04103 Leipzig, Germany.

2  Present address: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.

3  Khon Kaen University, Khon Kaen, Thailand.

4  National Cancer Institute, Bangkok, Thailand.

5  Department of Biological Sciences, School of Science, University of Tokyo, Tokyo, Japan.

Correspondence should be addressed to Mark Stoneking stoneking@eva.mpg.de
Genetic differences among human populations are usually larger for the Y chromosome than for mtDNA1, 2, 3. One possible explanation is the higher rate of female versus male migration due to the widespread phenomenon of patrilocality, in which the woman moves to her mate's residence after marriage. To test this hypothesis, we compare mtDNA and Y-chromosome variation in three matrilocal (in which the man moves to his mate's residence after marriage) and three patrilocal groups among the hill tribes of northern Thailand. Genetic diversity in these groups shows a striking correlation with residence pattern, supporting the role of sex-specific migration in influencing human genetic variation.


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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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