Fanconi anemia and breast cancer: what's the connection?
Hagop Youssoufian
Departments of Molecular and Human Genetics and Medicine, Baylor College of Medicine, Houston, Texas 77030, USA. hagopy@bcm.tmc.edu
BRCA1 activity may be regulated by the ubiquitin-modified form of the Fanconi anemia D2 protein. Other proteins involved in DNA repair and genomic stability that are also found in the same subnuclear compartments may be similarly regulated.
