DNA double-strand breaks: signaling, repair and the cancer connectionpp247 - 254 Kum Kum Khanna
& Stephen P. Jackson doi:10.1038/85798 Abstract|Full text|PDF
(252K)
Evolution of imprinting mechanisms: the battle of the sexes begins in the zygotepp255 - 256 Wolf Reik
& Jörn Walter doi:10.1038/85804 Full text|PDF
(30K)
Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygositypp257 - 258 Louis Lefebvre, Nancy Dionne, Jana Karaskova, Jeremy A. Squire
& Andras Nagy doi:10.1038/85808 Abstract|Full text|PDF
(141K)
Multigenic control of Listeria monocytogenes susceptibility in micepp259 - 260 Victor L. Boyartchuk, Karl W. Broman, Rebecca E. Mosher, Sarah E.F. D'Orazio, Michael N. Starnbach
& William F. Dietrich doi:10.1038/85812 Abstract|Full text|PDF
(609K)
|Supplementary Information
SPTLC1 is mutated in hereditary sensory neuropathy, type 1pp261 - 262 Khemissa Bejaoui, Chenyan Wu, Margaret D. Scheffler, Geoffry Haan, Peter Ashby, Lianchan Wu, Peter de Jong
& Robert H. Brown Jr. doi:10.1038/85817 Abstract|Full text|PDF
(38K)
|Supplementary Information
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein- (C/EBP), in acute myeloid leukemiapp263 - 270 Thomas Pabst, Beatrice U. Mueller, Pu Zhang, Hanna S. Radomska, Sailaja Narravula, Susanne Schnittger, Gerhard Behre, Wolfgang Hiddemann
& Daniel G. Tenen doi:10.1038/85820 Abstract|Full text|PDF
(703K)
Recombinational DNA double-strand breaks in mice precede synapsispp271 - 276 Shantha K. Mahadevaiah, James M.A. Turner, Frédéric Baudat, Emmy P. Rogakou, Peter de Boer, Josefa Blanco-Rodríguez, Maria Jasin, Scott Keeney, William M. Bonner
& Paul S. Burgoyne doi:10.1038/85830 Abstract|Full text|PDF
(1,720K)
See also:News and Views by Hunter et al.
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-B signalingpp277 - 285 Rainer Döffinger, Asma Smahi, Christine Bessia, Frédéric Geissmann, Jacqueline Feinberg, Anne Durandy, Christine Bodemer, Sue Kenwrick, Sophie Dupuis-Girod, Stéphane Blanche, Philip Wood, Smail Hadj Rabia, Denis J. Headon, Paul A. Overbeek, Françoise Le Deist, Steven M. Holland, Kiran Belani, Dinakantha S. Kumararatne, Alain Fischer, Ralph Shapiro, Mary Ellen Conley, Eric Reimund, Hermann Kalhoff, Mario Abinun, Arnold Munnich, Alain Israël, Gilles Courtois
& Jean-Laurent Casanova doi:10.1038/85837 Abstract|Full text|PDF
(594K)
A temperature-sensitive disorder in basal transcription and DNA repair in humanspp299 - 303 Wim Vermeulen, Suzanne Rademakers, Nicolaas G.J. Jaspers, Esther Appeldoorn, Anja Raams, Binie Klein, Wim J. Kleijer, Lars Kjærsgård Hansen
& Jan H.J. Hoeijmakers doi:10.1038/85864 Abstract|Full text|PDF
(1,061K)
Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type Ipp309 - 312 Jennifer L. Dawkins, Dennis J. Hulme, Sonal B. Brahmbhatt, Michaela Auer-Grumbach
& Garth A. Nicholson doi:10.1038/85879 Abstract|Full text|PDF
(97K)
|Supplementary Information
Constitutively activating mutation in WASP causes X-linked severe congenital neutropeniapp313 - 317 Koenraad Devriendt, Annette S. Kim, Gert Mathijs, Suzanna G.M. Frints, Marianne Schwartz, Joost J. Van den Oord, Gregor E.G. Verhoef, Marc A. Boogaerts, Jean-Pierre Fryns, Daoqi You, Michael K. Rosen
& Peter Vandenberghe doi:10.1038/85886 Abstract|Full text|PDF
(349K)
Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid statespp318 - 321 Philip Schaner, Neil Richards, Anish Wadhwa, Ivona Aksentijevich, Daniel Kastner, Priscilla Tucker
& Deborah Gumucio doi:10.1038/85893 Abstract|Full text|PDF
(444K)
|Supplementary Information
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndromepp322 - 326 Jacky Guy, Brian Hendrich, Megan Holmes, Joanne E. Martin
& Adrian Bird doi:10.1038/85899 Abstract|Full text|PDF
(223K)
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in micepp327 - 331 Richard Z. Chen, Schahram Akbarian, Matthew Tudor
& Rudolf Jaenisch doi:10.1038/85906 Abstract|Full text|PDF
(732K)
Open-reading-frame sequence tags (OSTs) support the existence of at least 17,300 genes in C. eleganspp332 - 336 Jérôme Reboul, Philippe Vaglio, Nia Tzellas, Nicolas Thierry-Mieg, Troy Moore, Cindy Jackson, Tadasu Shin-i, Yuji Kohara, Danielle Thierry-Mieg, Jean Thierry-Mieg, Hongmei Lee, Joseph Hitti, Lynn Doucette-Stamm, James L. Hartley, Gary F. Temple, Michael A. Brasch, Jean Vandenhaute, Philippe E. Lamesch, David E. Hill
& Marc Vidal doi:10.1038/85913 Abstract|Full text|PDF
(595K)
|Supplementary Information
Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genomepp337 - 340 Shuba Gopal, Mark Schroeder, Ursula Pieper, Alexander Sczyrba, Gulriz Aytekin-Kurban, Stefan Bekiranov, J. Eduardo Fajardo, Narayanan Eswar, Roberto Sanchez, Andrej Sali
& Terry Gaasterland doi:10.1038/85922 Abstract|Full text|PDF
(49K)
Maternal methylation imprints on human chromosome 15 are established during or after fertilizationpp341 - 344 Osman El-Maarri, Karin Buiting, Edwin G. Peery, Peter M. Kroisel, Basak Balaban, Klaus Wagner, Bulent Urman, Julia Heyd, Christina Lich, Camilynn I. Brannan, Jörn Walter
& Bernhard Horsthemke doi:10.1038/85927 Abstract|Full text|PDF
(934K)
|Supplementary Information
Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPPp345 doi:10.1038/85933 Full text|PDF
(46K)
Linkage disequilibrium of a type 1 diabetes susceptibility gene with regulatory IL12B allelesp346 doi:10.1038/85936 Full text|PDF
(20K)
-H2AX illuminates meiosis
(C/EBP
B signaling
