Prediction of protein interactions: metabolic enzymes are frequently involved in gene fusionpp141 - 142 Sophia Tsoka
& Christos A. Ouzounis doi:10.1038/79847 Full text|PDF
(396K)
Mutations in GJB6 cause hidrotic ectodermal dysplasiapp142 - 144 Jérôme Lamartine, Guilherme Munhoz Essenfelder, Zoha Kibar, Isabelle Lanneluc, Edwige Callouet, Dalila Laoudj, Gilles Lemaître, Colette Hand, Susan J. Hayflick, Jonathan Zonana, Stylianos Antonarakis, Uppala Radhakrishna, David P. Kelsell, Arnold L. Christianson, Amandine Pitaval, Vazken Der Kaloustian, Clarke Fraser, Claudine Blanchet-Bardon, Guy A. Rouleau
& Gilles Waksman doi:10.1038/79851 Full text|PDF
(448K)
A view of Neandertal genetic diversitypp144 - 146 Matthias Krings, Cristian Capelli, Frank Tschentscher, Helga Geisert, Sonja Meyer, Arndt von Haeseler, Karl Grossschmidt, Göran Possnert, Maja Paunovic
& Svante Pääbo doi:10.1038/79855 Full text|PDF
(96K)
|Supplementary Information
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating -catenin/TCF signallingpp146 - 147 Wanguo Liu, Xiangyang Dong, Ming Mai, Ratnam S. Seelan, Ken Taniguchi, Kausilia K. Krishnadath, Kevin C. Halling, Julie M. Cunningham, Chiping Qian, Eric Christensen, Patrick C. Roche, David I. Smith
& Stephen N. Thibodeau doi:10.1038/79859 Full text|PDF
(85K)
How many diseases does it take to map a gene with SNPs?pp151 - 157 Kenneth M. Weiss
& Joseph D. Terwilliger doi:10.1038/79866 Abstract|Full text|PDF
(194K)
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellituspp163 - 175 Yukio Horikawa, Naohisa Oda, Nancy J. Cox, Xiangquan Li, Marju Orho-Melander, Manami Hara, Yoshinori Hinokio, Tom H. Lindner, Hirosato Mashima, Peter E.H. Schwarz, Laura del Bosque-Plata, Yohko Horikawa, Yukie Oda, Issei Yoshiuchi, Susan Colilla, Kenneth S. Polonsky, Shan Wei, Patrick Concannon, Naoko Iwasaki, Jan Schulze, Leslie J. Baier, Clifton Bogardus, Leif Groop, Eric Boerwinkle, Craig L. Hanis
& Graeme I. Bell doi:10.1038/79876 Abstract|Full text|PDF
(250K)
|Supplementary Information See also:News and Views by Altshuler et al.
Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotespp176 - 181 Kimiko Inoue, Kazuto Nakada, Atsuo Ogura, Kotoyo Isobe, Yu-ichi Goto, Ikuya Nonaka
& Jun-Ichi Hayashi doi:10.1038/82826 Abstract|Full text|PDF
(1,939K)
See also:News and Views by Shoubridge
A computational analysis of whole-genome expression data reveals chromosomal
domains of gene expressionpp183 - 186 Barak A. Cohen, Robi D. Mitra, Jason D. Hughes
& George M. Church doi:10.1038/79896 Abstract|Full text|PDF
(550K)
Transposition of maize Ac/Ds transposable elements in the yeast Saccharomyces cerevisiaepp187 - 190 Clifford F. Weil
& Reinhard Kunze doi:10.1038/82827 Abstract|Full text|PDF
(204K)
Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10pp191 - 194 Tohru Matsuura, Takanori Yamagata, Daniel L. Burgess, Astrid Rasmussen, Raji P. Grewal, Kei Watase, Mehrdad Khajavi, Alanna E. McCall, Caleb F. Davis, Lan Zu, Madhureeta Achari, Stefan M. Pulst, Elisa Alonso, Jeffrey L. Noebels, David L. Nelson, Huda Y. Zoghbi
& Tetsuo Ashizawa doi:10.1038/79911 Abstract|Full text|PDF
(367K)
The mouse fidgetin gene defines a new role for AAA family proteins in mammalian developmentpp198 - 202 Gregory A. Cox, Connie L. Mahaffey, Arne Nystuen, Verity A. Letts
& Wayne N. Frankel doi:10.1038/79923 Abstract|Full text|PDF
(1,274K)
Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19pp203 - 206 Miguel Constância, Wendy Dean, Susana Lopes, Tom Moore, Gavin Kelsey
& Wolf Reik doi:10.1038/79930 Abstract|Full text|PDF
(297K)
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophypp207 - 210 Cécile Delettre, Guy Lenaers, Jean-Michel Griffoin, Nadine Gigarel, Corinne Lorenzo, Pascale Belenguer, Laetitia Pelloquin, Josiane Grosgeorge, Claude Turc-Carel, Eric Perret, Catherine Astarie-Dequeker, Laetitia Lasquellec, Bernard Arnaud, Bernard Ducommun, Josseline Kaplan
& Christian P. Hamel doi:10.1038/79936 Abstract|Full text|PDF
(2,365K)
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal
dominant optic atrophy linked to chromosome 3q28pp211 - 215 Christiane Alexander, Marcela Votruba, Ulrike E.A. Pesch, Dawn L. Thiselton, Simone Mayer, Anthony Moore, Miguel Rodriguez, Ulrich Kellner, Beate Leo-Kottler, Georg Auburger, Shomi S. Bhattacharya
& Bernd Wissinger doi:10.1038/79944 Abstract|Full text|PDF
(804K)
Effective targeted gene 'knockdown' in zebrafishpp216 - 220 Aidas Nasevicius
& Stephen C. Ekker doi:10.1038/79951 Abstract|Full text|PDF
(811K)
Human-mouse genome comparisons to locate regulatory sitespp225 - 228 Wyeth W. Wasserman, Michael Palumbo, William Thompson, James W. Fickett
& Charles E. Lawrence doi:10.1038/79965 Abstract|Full text|PDF
(249K)
Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse developmentpp229 - 232 Wanting Xu, Diane G. Edmondson, Yvonne A. Evrard, Maki Wakamiya, Richard R. Behringer
& Sharon Y. Roth doi:10.1038/79973 Abstract|Full text|PDF
(2,968K)
Genome-wide analysis of single-nucleotide polymorphisms in human expressed
sequencespp233 - 236 Kris Irizarry, Vlad Kustanovich, Cheng Li, Nik Brown, Stanley Nelson, Wing Wong
& Christopher J. Lee doi:10.1038/79981 Abstract|Full text|PDF
(362K)
|Supplementary Information
Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase genepp237 - 241 Tomoya O. Akama, Kohji Nishida, Jun Nakayama, Hitoshi Watanabe, Kouichi Ozaki, Takahiro Nakamura, Atsuyoshi Dota, Satoshi Kawasaki, Yoshitsugu Inoue, Naoyuki Maeda, Shuji Yamamoto, Tsutomu Fujiwara, Eugene J.-M.A. Thonar, Yoshikazu Shimomura, Shigeru Kinoshita, Akira Tanigami
& Michiko N. Fukuda doi:10.1038/79987 Abstract|Full text|PDF
(406K)
|Supplementary Information
Biochemical defects in ABCR protein variants associated with human retinopathiespp242 - 246 Hui Sun, Philip M. Smallwood
& Jeremy Nathans doi:10.1038/79994 Abstract|Full text|PDF
(339K)
Mutations in ARHGEF6, encoding a guanine nucleotide exchange factor for Rho GTPases, in patients with X-linked mental retardationpp247 - 250 Kerstin Kutsche, Helger Yntema, Alexander Brandt, Inka Jantke, Hans Gerd Nothwang, Ulrike Orth, Maria G. Boavida, Dezsö David, Jamel Chelly, Jean-Pierre Fryns, Claude Moraine, Hans-Hilger Ropers, Ben C.J. Hamel, Hans van Bokhoven
& Andreas Gal doi:10.1038/80002 Abstract|Full text|PDF
(214K)
-catenin/TCF signalling
