Division of Human Gene Therapy, Departments of Medicine,
Pathology and Surgery, and Gene Therapy Center, University of Alabama at Birmingham
, Birmingham, Alabama 35294, USA
.david.curiel@ccc.uab.edu
Rational vector design is pivotal for successful human gene therapy
and the application of high-throughput methods may provide a means for the
efficient realization of vectors with desired properties. A method involving
DNA shuffling represents a powerful new paradigm in this regard.
