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Brief Communication
Nature Genetics 25, 254–255 (1 July 2000) | doi:10.1038/76996
Hepatocyte migration during liver development requires Prox1
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Abstract
Several genes are required during the early phases of liver specification, proliferation and differentiation. Here we report that Prox1 is required for hepatocyte migration. Loss of Prox1 leads to formation of a smaller liver with a reduced population of clustered hepatocytes surrounded by a laminin-rich basal membrane.
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