Are (CTG)n expansions at the SCA8 locus rare polymorphisms?p213 Giovanni Stevanin, Alexandra Herman, Alexandra Dürr, Carla Jodice, Marina Frontali, Yves Agid
& Alexis Brice doi:10.1038/73408 Full text|PDF
(95K)
Large, expanded repeats in SCA8 are not confined to patients with cerebellar ataxiapp214 - 215 Paul F. Worth, Henry Houlden, Paola Giunti, Mary B. Davis
& Nicholas W. Wood doi:10.1038/73411 Full text|PDF
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Reply—p215 Melinda L. Moseley, Lawrence J. Schut, Thomas D. Bird, John W. Day
& Laura P.W. Ranum doi:10.1038/73415 Full text|PDF
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Analysing complex genetic traits with chromosome substitution strains
pp221 - 225 Joseph H. Nadeau, Jonathan B. Singer, Angabin Matin
& Eric S. Lander doi:10.1038/73427 Abstract|Full text|PDF
(124K)
Systematic variation in gene expression patterns in human cancer cell
linespp227 - 235 Douglas T. Ross, Uwe Scherf, Michael B. Eisen, Charles M. Perou, Christian Rees, Paul Spellman, Vishwanath Iyer, Stefanie S. Jeffrey, Matt Van de Rijn, Mark Waltham, Alexander Pergamenschikov, Jeffrey C.F. Lee, Deval Lashkari, Dari Shalon, Timothy G. Myers, John N. Weinstein, David Botstein
& Patrick O. Brown doi:10.1038/73432 Abstract|Full text|PDF
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A gene expression database for the molecular pharmacology of cancerpp236 - 244 Uwe Scherf, Douglas T. Ross, Mark Waltham, Lawrence H. Smith, Jae K. Lee, Lorraine Tanabe, Kurt W. Kohn, William C. Reinhold, Timothy G. Myers, Darren T. Andrews, Dominic A. Scudiero, Michael B. Eisen, Edward A. Sausville, Yves Pommier, David Botstein, Patrick O. Brown
& John N. Weinstein doi:10.1038/73439 Abstract|Full text|PDF
(956K)
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AXIN1 mutations in hepatocellular carcinomas, and growth suppression
in cancer cells by virus-mediated transfer of AXIN1pp245 - 250 Seiji Satoh, Yataro Daigo, Yoichi Furukawa, Tatsushi Kato, Nobutomo Miwa, Tadashi Nishiwaki, Teru Kawasoe, Hideyuki Ishiguro, Manabu Fujita, Takashi Tokino, Yo Sasaki, Shingi Imaoka, Masaru Murata, Takashi Shimano, Yoshio Yamaoka
& Yusuke Nakamura doi:10.1038/73448 Abstract|Full text|PDF
(2,384K)
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Mutations in ACTN4, encoding -actinin-4, cause familial
focal segmental glomerulosclerosispp251 - 256 Joshua M. Kaplan, Sung H Kim, Kathryn N. North, Helmut Rennke, Lori A, Hui-Qi Tong, Beverly J. Mathis, José-Carlos Rodríguez-Pérez, Philip G. Allen, Alan H. Beggs
& Martin R. Pollak doi:10.1038/73456 Abstract|Full text|PDF
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Evidence for gene transfer and expression of factor IX in haemophilia
B patients treated with an AAV vectorpp257 - 261 Mark A. Kay, Catherine S. Manno, Margaret V. Ragni, Peter J. Larson, Linda B. Couto, Alan McClelland, Bertil Glader, Amy J. Chew, Shing J , Roland W. Herzog, Valder Arruda, Fred Johnson, Ciaran Scallan, Erik Skarsgard, Alan W. Flake
& Katherine A. High doi:10.1038/73464 Abstract|Full text|PDF
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Regulation of left-right patterning in mice by growth/differentiation
factor-1pp262 - 265 Christopher T. Rankin, Tracie Bunton, Ann M. Lawler
& Se-Jin Lee doi:10.1038/73472 Abstract|Full text|PDF
(770K)
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited
mutation in GATA1pp266 - 270 Kim E. Nichols, John D. Crispino, Mortimer Poncz, James G. White, Stuart H. Orkin, John M. Maris
& Mitchell J. Weiss doi:10.1038/73480 Abstract|Full text|PDF
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Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate developmentpp271 - 274 Thomas M. DeChiara, Robert B. Kimble, William T. Poueymirou, Jose Rojas, Piotr Masiakowski, David M. Valenzuela
& George D. Yancopoulos doi:10.1038/73488 Abstract|Full text|PDF
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Dominant mutations in ROR2, encoding an orphan receptor tyrosine
kinase, cause brachydactyly type Bpp275 - 278 Michael Oldridge, Ana M , Monika Maringa, Peter Propping, Sahar Mansour, Christine Pollitt, Thomas M. DeChiara, Robert B. Kimble, David M. Valenzuela, George D. Yancopoulos
& Andrew O.M. Wilkie doi:10.1038/73495 Abstract|Full text|PDF
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The gamete fusion process is defective in eggs of Cd9-deficient micepp279 - 282 Keisuke Kaji, Shoji Oda, Tomohide Shikano, Tatsuya Ohnuki, Yoshikatsu Uematsu, Junko Sakagami, Norihiro Tada, Shunichi Miyazaki
& Akira Kudo doi:10.1038/73502 Abstract|Full text|PDF
(442K)
Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental
dysostosispp283 - 286 Victor L. Ruiz-Perez, Susan E. Ide, Tim M. Strom, Bettina Lorenz, David Wilson, Kathryn Woods, Lynn King, Clair Francomano, Peter Freisinger, Stephanie Spranger, Bruno Marino, Bruno Dallapiccola, Michael Wright, Thomas Meitinger, Mihael H. Polymeropoulos
& Judith Goodship doi:10.1038/73508 Abstract|Full text|PDF
(490K)
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Rnx deficiency results in congenital central hypoventilationpp287 - 290 Senji Shirasawa, Akiko Arata, Hiroshi Onimaru, Kevin A. Roth, Gary A. Brown, Susan Horning, Satoru Arata, Koji Okumura, Takehiko Sasazuki
& Stanley J. Korsmeyer doi:10.1038/73516 Abstract|Full text|PDF
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The gene MAPK8IP1, encoding islet-brain-1, is a candidate for
type 2 diabetespp291 - 295 Gérard Waeber, Jérôme Delplanque, Christophe Bonny, Vincent Mooser, Myriam Steinmann, Christian Widmann, Anne Maillard, Judith Miklossy, Christian Dina, El H Hani, Gérard Waeber, Jérôme Delplanque, Nathalie Vionnet, Pascal Nicod, Philippe Boutin
& Philippe Froguel doi:10.1038/73523 Abstract|Full text|PDF
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Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesispp296 - 299 Binbin Chen, Roderick T. Bronson, Lori D. Klaman, Thomas G. Hampton, Ju-feng Wang, Patricia J. Green, Terry Magnuson, Pamela S. Douglas, James P. Morgan
& Benjamin G. Neel doi:10.1038/73528 Abstract|Full text|PDF
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Mutations truncating the EP300 acetylase in human cancerspp300 - 303 Simon A. Gayther, Sarah J. Batley, Lori Linger, Andy Bannister, Karen Thorpe, Suet-Feung Chin, Yataro Daigo, Paul Russell, Annie Wilson, Heidi M. Sowter, Joy D.A. Delhanty, Bruce A.J. Ponder, Tony Kouzarides
& Carlos Caldas doi:10.1038/73536 Abstract|Full text|PDF
(452K)
|Supplementary Information
Mice deficient in Abl are osteoporotic and have defects in osteoblast
maturationpp304 - 308 Baojie Li, Sharon Boast, Kenia de los Santos, Ira Schieren, Marisol Quiroz, Steven L. Teitelbaum, M. M
& Stephen P. Goff doi:10.1038/73542 Abstract|Full text|PDF
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Mekk3 is essential for early embryonic cardiovascular developmentpp309 - 313 Jianhua Yang, Melynda Boerm, Marya McCarty, Corazon Bucana, Isaiah J. Fidler, Yuan Z J
& Bing Su doi:10.1038/73550 Abstract|Full text|PDF
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Genotype-based screen for ENU-induced mutations in mouse embryonic stem cellspp314 - 317 Yijing Chen, Della Yee, Katherine Dains, Aurobindo Chatterjee, James Cavalcoli, Elizabeth Schneider, Jinsop Om, Richard P. Woychik
& Terry Magnuson doi:10.1038/73557 Abstract|Full text|PDF
(168K)
Mouse mutants from chemically mutagenized embryonic stem cellspp318 - 321 Robert J. Munroe, Rebecca A. Bergstrom, Qing Y , Brian Libby, Richard Smith, Simon W.M. John, Kerry J. Schimenti, Victoria L. Browning
& John C. Schimenti doi:10.1038/73563 Abstract|Full text|PDF
(659K)
-actinin-4, cause familial
focal segmental glomerulosclerosis
