Nuclear transfer into mouse zygotespp108 - 109 Teruhiko Wakayama, Hiroyuki Tateno, Peter Mombaerts
& Ryuzo Yanagimachi doi:10.1038/72749 Full text|PDF
(398K)
Generation of mice from wild-type and targeted ES cells by nuclear cloningpp109 - 110 William M. Rideout III, Teruhiko Wakayama, Anton Wutz, Kevin Eggan, Laurie Jackson-Grusby, Jessica Dausman, Ryuzo Yanagimachi
& Rudolf Jaenisch doi:10.1038/72753 Full text|PDF
(192K)
Gene-target recognition among members of the Myc superfamily and implications
for oncogenesispp113 - 119 Rónán C. O'Hagan, Nicole Schreiber-Agus, Ken Chen, Gregory David, Jeffrey A. Engelman, Richard Schwab, Leila Alland, Cole Thomson, Donald R. Ronning, James C. Sacchettini, Paul Meltzer
& Ronald A. DePinho doi:10.1038/72761 Abstract|Full text|PDF
(1,061K)
ARSACS, a spastic ataxia common in northeastern Québec, is caused
by mutations in a new gene encoding an 11.5-kb ORFpp120 - 125 James C. Engert, Pierre Bérubé, Jocelyne Mercier, Carole Doré, Pierre Lepage, Bing Ge, Jean-Pierre Bouchard, Jean Mathieu, Serge B. Melançon, Martin Schalling, Eric S. Lander, Kenneth Morgan, Thomas J. Hudson
& Andrea Richter doi:10.1038/72769 Abstract|Full text|PDF
(777K)
Mutation of a nuclear receptor gene, NR2E3, causes
enhanced S cone syndrome, a disorder of retinal cell fatepp127 - 131 Neena B. Haider, Samuel G. Jacobson, Artur V. Cideciyan, Ruth Swiderski, Luan M. Streb, Charles Searby, Gretel Beck, Robin Hockey, David B. Hanna, Susan Gorman, David Duhl, Rivka Carmi, Jean Bennett, Richard G. Weleber, Gerald A. Fishman, Alan F. Wright, Edwin M. Stone
& Val C. Sheffield doi:10.1038/72777 Abstract|Full text|PDF
(974K)
See also:News and Views by Cepko
Aberrant CpG-island methylation has non-random and tumour-type−specific
patternspp132 - 138 Joseph F. Costello, Michael C. Frühwald, Dominic J. Smiraglia, Laura J. Rush, Gavin P. Robertson, Xin Gao, Fred A. Wright, Jamison D. Feramisco, Päivi Peltomäki, James C. Lang, David E. Schuller, Li Yu, Clara D. Bloomfield, Michael A. Caligiuri, Allan Yates, Ryo Nishikawa, H.-J. Su Huang, Nicholas J. Petrelli, Xueli Zhang, M. S. O, William A. Held, Webster K. Cavenee
& Christoph Plass doi:10.1038/72785 Abstract|Full text|PDF
(797K)
See also:News and Views by Eng et al.
Targeted disruption of Otog results in deafness and severe imbalance
pp139 - 143 Marie-Christine Simmler, Martine Cohen-Salmon, Aziz El-Amraoui, Laurent Guillaud, Jean-Claude Benichou, Christine Petit
& Jean-Jacques Panthier doi:10.1038/72793 Abstract|Full text|PDF
(1,037K)
See also:News and Views by Steel
A genome-wide survey of RAS transformation targetspp144 - 152 Johannes Zuber, Oleg I. Tchernitsa, Bernd Hinzmann, Anne-Chantal Schmitz, Martin Grips, Martin Hellriegel, Christine Sers, André Rosenthal
& Reinhold Schäfer doi:10.1038/72799 Abstract|Full text|PDF
(341K)
|Supplementary Information
LMNA, encoding lamin A/C, is mutated in partial lipodystrophy
pp153 - 156 Sue Shackleton, David J. Lloyd, Stephen N.J. Jackson, Richard Evans, Martinus F. Niermeijer, Baldev M. Singh, Hartmut Schmidt, Georg Brabant, Sudesh Kumar, Paul N. Durrington, Simon Gregory, Stephen O'Rahilly
& Richard C. Trembath doi:10.1038/72807 Abstract|Full text|PDF
(245K)
See also:News and Views by Flier
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertilitypp157 - 162 Peter Blume-Jensen, Guoqiang Jiang, Robert Hyman, Kuo-Fen Lee, Stephen O'Gorman
& Tony Hunter doi:10.1038/72814 Abstract|Full text|PDF
(1,262K)
Limb-girdle muscular dystrophy type 2G is caused by mutations in the
gene encoding the sarcomeric protein telethoninpp163 - 166 Eloisa S. Moreira, Tim J. Wiltshire, Georgine Faulkner, Antje Nilforoushan, Mariz Vainzof, Oscar T. Suzuki, Giorgio Valle, Roger Reeves, Mayana Zatz, M. R. Passos-Bueno
& Dieter E. Jenne doi:10.1038/72822 Abstract|Full text|PDF
(797K)
A new gene involved in X-linked mental retardation identified by analysis
of an X;2 balanced translocationpp167 - 170 Ramzi Zemni, Thierry Bienvenu, Marie C. Vinet, Aziz Sefiani, Alain Carrié, Pierre Billuart, Nathalie McDonell, Philippe Couvert, Fiona Francis, Philippe Chafey, Fabien Fauchereau, Gaelle Friocourt, Vincent des Portes, Anna Cardona, Suzanna Frints, Alfonse Meindl, Oliver Brandau, Nathalie Ronce, Claude Moraine, Han van Bokhoven, Hans H. Ropers, Ralf Sudbrak, Axel Kahn, Jean P Fryns, Cherif Beldjord
& Jamel Chelly doi:10.1038/72829 Abstract|Full text|PDF
(544K)
|Supplementary Information
A role for Smad6 in development and homeostasis of the cardiovascular systempp171 - 174 Katherine M. Galvin, Michael J. Donovan, Catherine A. Lynch, Ronald I. Meyer, Richard J. Paul, John N. Lorenz, Victoria Fairchild-Huntress, Kristen L. Dixon, Judy H. Dunmore, Michael A. Gimbrone Jr, Dean Falb
& Dennis Huszar doi:10.1038/72835 Abstract|Full text|PDF
(631K)
Fus deficiency in mice results in defective B-lymphocyte development
and activation, high levels of chromosomal instability and perinatal death
pp175 - 179 Geoffrey G. Hicks, Nagendra Singh, Abudi Nashabi, Sabine Mai, Gracjan Bozek, Ludger Klewes, Djula Arapovic, Erica K. White, Mark J. Koury, Eugene M. Oltz, Luc Van Kaer
& H. E. Ruley doi:10.1038/72842 Abstract|Full text|PDF
(231K)
Heritable and inducible genetic interference by double-stranded RNA encoded
by transgenespp180 - 183 Nektarios Tavernarakis, Shi L. Wang, Maxim Dorovkov, Alexey Ryazanov
& Monica Driscoll doi:10.1038/72850 Abstract|Full text|PDF
(336K)
Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation
pp184 - 187 Koichi Matsuo, Jane M. Owens, Martin Tonko, Candace Elliott, Timothy J. Chambers
& Erwin F. Wagner doi:10.1038/72855 Abstract|Full text|PDF
(458K)
Mutations in the gene encoding peroxisomal -methylacyl-CoA racemase cause adult-onset sensory motor neuropathypp188 - 191 Sacha Ferdinandusse, Simone Denis, Peter T. Clayton, Andrew Graham, John E. Rees, John T. Allen, Brendan N. McLean, Ann Y. Brown, Peter Vreken, Hans R. Waterham
& Ronald J.A. Wanders doi:10.1038/72861 Abstract|Full text|PDF
(180K)
Transport of lipids from Golgi to plasma membrane is defective in Tangier
disease patients and Abc1-deficient micepp192 - 196 Evelyn Orsó, Cyril Broccardo, Wolfgang E. Kaminski, Alfred Böttcher, Gerhard Liebisch, Wolfgang Drobnik, Alexandra Götz, Olivier Chambenoit, Wendy Diederich, Thomas Langmann, Thilo Spruss, Marie-Francoise Luciani, Gregor Rothe, Karl J. Lackner, Giovanna Chimini
& Gerd Schmitz doi:10.1038/72869 Abstract|Full text|PDF
(567K)
Localization to Xq27 of a susceptibility gene for testicular germ-cell tumourspp197 - 200 Elizabeth A. Rapley, Gillian P. Crockford, Dawn Teare, Patrick Biggs, Sheila Seal, Rita Barfoot, Sandra Edwards, Rifat Hamoudi, Ketil Heimdal, Sophie D. Fosså, Kathy Tucker, Jenny Donald, Felicity Collins, Michael Friedlander, David Hogg, Paul Goss, Axel Heidenreich, Wilma Ormiston, Peter A. Daly, David Forman, Timothy D. Oliver, Michael Leahy, Robert Huddart, Colin S. Cooper, Julia G. Bodmer, Douglas F. Easton, Michael R. Stratton
& D. Timothy Bishop doi:10.1038/72877 Abstract|Full text|PDF
(414K)
-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
