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TY  - JOUR
AU  - Linnane, A.W.
AU  - Marzuki, S.
AU  - Ozawa, T.
AU  - Tanaka, M.
TI  - Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
JO  - Lancet
PY  - 1989///
VL  - 3
SP  - 642
EP  - 645
M3  - 10.1016/S0140-6736(89)92145-4
N1  - 10.1016/S0140-6736(89)92145-4
UR  - http://dx.doi.org/10.1016/S0140-6736(89)92145-4
ER  - 

TY  - JOUR
AU  - Wallace, D.C.
TI  - Mitochondrial genetics: A paradigm for ageing and degenerative diseases?
JO  - Science
PY  - 1992///
VL  - 256
SP  - 628
EP  - 632
ER  - 

TY  - JOUR
AU  - Wallace, D.C.
TI  - Diseases of the mitochondrial DNA
JO  - Ann. Rev. Biochem.
PY  - 1992///
VL  - 61
SP  - 1175
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M3  - 10.1146/annurev.bi.61.070192.005523
N1  - 10.1146/annurev.bi.61.070192.005523
UR  - http://dx.doi.org/10.1146/annurev.bi.61.070192.005523
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TY  - JOUR
AU  - Muller-Hocker, J.
TI  - Cytochrome-c-oxidase deficient cardiomyocytes in the human heart
JO  - Am. J. Pathol.
PY  - 1989///
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TY  - JOUR
AU  - Muller-Hocker, J.
TI  - Cytochrome c oxidase deficient fibres in the limb muscle and diaphragm of man without muscular disease: An age-related alteration
JO  - J. neurol. Sci.
PY  - 1990///
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UR  - http://dx.doi.org/10.1016/0022-510X(90)90006-9
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TY  - JOUR
AU  - Trounce, I.
AU  - Byrne, E.
AU  - Marzuki, S.
TI  - Decline in skeletal muscle mitochondrial respiratory chain function: Possible factor in aging
JO  - Lancet
PY  - 1989///
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M3  - 10.1016/S0140-6736(89)92143-0
N1  - 10.1016/S0140-6736(89)92143-0
UR  - http://dx.doi.org/10.1016/S0140-6736(89)92143-0
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TY  - JOUR
AU  - Yen, T.C.
AU  - Chen, Y.S.
AU  - King, K.L.
AU  - Yeh, S.H.
AU  - Wei, Y.H.
TI  - Liver mitochondrial respiratory functions decline with age
JO  - Biochem. Biophys. Res. Commun.
PY  - 1989///
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TY  - JOUR
AU  - Piko, L.
AU  - Hougham, A.J.
AU  - Bulpitt, K.J.
TI  - Studies of sequence heterogeneity of mitochondrial DNA from rat and mouse tissues: Evidence for an increased frequency of deletions/additions with aging
JO  - Mech. ageing Devl.
PY  - 1988///
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N1  - 10.1016/0047-6374(88)90037-1
UR  - http://dx.doi.org/10.1016/0047-6374(88)90037-1
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TY  - JOUR
AU  - Katayama, M.
TI  - Deleted mitochondrial DNA in the skeletal muscle of aged individuals
JO  - Biochem. Int.
PY  - 1991///
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SP  - 47
EP  - 56
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TY  - JOUR
AU  - Yen, T.C.
AU  - Su, J.H.
AU  - King, K.L.
AU  - Wei, Y.H.
TI  - Ageing-associated 5 kb deletion in human liver mitochondrial DNA
JO  - Biochem. Biophys. Res. Commun.
PY  - 1991///
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TY  - JOUR
AU  - Zhang, C.
AU  - Baumer, A.
AU  - Maxwell, R.J.
AU  - Linnane, A.W.
AU  - Nagley, P.
TI  - Multiple mitochondrial DNA deletions in an elderly human individual
JO  - FEBS Lett.
PY  - 1992///
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M3  - 10.1016/0014-5793(92)80321-7
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UR  - http://dx.doi.org/10.1016/0014-5793(92)80321-7
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TY  - JOUR
AU  - Cortopassi, G.A.
AU  - Arnheim, N.
TI  - Detection of a specific mitochondrial DNA deletion in tissues of older humans
JO  - Nucleic Acid Res.
PY  - 1990///
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TY  - JOUR
AU  - Corral-Debrinski, M.
TI  - Hypoxemia is associated with mitochondrial DNA damage and gene induction: Implications for cardiac disease
JO  - JAMA
PY  - 1991///
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M3  - 10.1001/jama.266.13.1812
N1  - 10.1001/jama.266.13.1812
UR  - http://dx.doi.org/10.1001/jama.266.13.1812
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TY  - JOUR
AU  - Corral-Debrinski, M.
AU  - Shoffner, J.M.
AU  - Lott, M.T.
AU  - Wallace, D.C.
TI  - Association of mitochondrial DNA damage with ageing and coronary atherosclerotic disease
JO  - Mutat. Res.
PY  - 1992///
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M3  - 10.1016/0921-8734(92)90021-G
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UR  - http://dx.doi.org/10.1016/0921-8734(92)90021-G
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TY  - JOUR
AU  - Hattori, K.
TI  - Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to presbycardia
JO  - Am. Heart J.
PY  - 1991///
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UR  - http://dx.doi.org/10.1016/0002-8703(91)90020-I
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TY  - GEN
AU  - Miquel, J.
AU  - Fleming, J.E.
TI  - Free Radicals, Aging, and Degenerative diseases
PY  - 1986///
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AU  - Miquel, J.
TI  - An integrated theory of ageing as the result of mitochondrial DNA mutation in differentiated cells
JO  - Arch. Gerontol. Geriatr.
PY  - 1991///
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UR  - http://dx.doi.org/10.1016/0167-4943(91)90022-I
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TY  - JOUR
AU  - Richter, C.
AU  - Park, J.W.
AU  - Ames, B.N.
TI  - Normal oxidative damage to mitochondrial and nuclear DNA is extensive
JO  - Proc. natn. Acad. Sci. U.S.A.
PY  - 1988///
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AU  - Fukunaga, M.
AU  - Yielding, K.L.
TI  - Fate during cell growth of yeast mitochondria and nuclear DNA after photolytic attachment of the monoazide analog of ethidium
JO  - Biochem. Biophys. Res. Commun.
PY  - 1979///
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AU  - Bandy, B.
AU  - Davison, A.J.
TI  - Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and ageing?
JO  - Mutat. Res.
PY  - 1990///
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UR  - http://dx.doi.org/10.1016/0891-5849(90)90152-9
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AU  - McCord, J.M.
TI  - Free radicals and myocardial ischemia : overview and outlook
JO  - Free Rad. Biol. Med.
PY  - 1988///
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UR  - http://dx.doi.org/10.1016/0891-5849(88)90005-6
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AU  - Drayer, B.P.
AU  - Burger, P.
AU  - Darwin, R.
TI  - Magnetic resonance imaging of brain iron
JO  - Am. J. Neuroradiol.
PY  - 1986///
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AU  - Drayer, B.P.
TI  - Imaging of the ageing brain Part I. Normal findings
JO  - Radiology
PY  - 1988///
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AU  - Goldstein, S.
AU  - Reivich, M.
TI  - Cerebral blood flow and metabolism in ageing and dementia
JO  - Clin. Neuropharm.
PY  - 1991///
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AU  - Chawluk, J.B.
AU  - Alavi, A.
AU  - Jamieson, D.G.
TI  - Changes in local cerebral glucose metabolism with normal ageing: the effect of cardiovascular and systemic health factors
JO  - J. Cereb. Blood Flow Metab.
PY  - 1987///
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AU  - Ditter, S.M.
AU  - Mirra, S.S.
TI  - Neuropathological and clinical features of Parkinson's disease in Alzheimer's diseases patients
JO  - Neurology
PY  - 1987///
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TY  - JOUR
AU  - Mirra, S.S.
TI  - The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathological assessment of Alzheimer's disease
JO  - Neurology
PY  - 1991///
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AU  - Wallace, D.C.
AU  - Lott, M.T.
AU  - Torroni, A.
AU  - Shoffner, J.M.
TI  - Report of the committee on human mitochondrial DNA
JO  - Cytogenet. Cell Genet.
PY  - 1991///
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AU  - Shoffner, J.M.
TI  - Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome is associated with a mtDNA deletion: A slip-replication model and metabolic therapy
JO  - Proc. natn. Acad. Sci. U.S.A.
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TI  - Multiple mitochondrial DNA deletions exist in cardiomyocytes of patients with hypertrophic or dilated cardiomyopathy
JO  - Biochem. Biophys. Res. Commun.
PY  - 1990///
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AU  - McGeer, P.L.
AU  - McGeer, E.G.
AU  - Suzuki, J.S.
TI  - ageing and extrapyramidal function
JO  - Arch. Neurol.
PY  - 1977///
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AU  - Morris, J.C.
AU  - McManus, D.Q.
TI  - The neurology of ageing: Normal versus pathological changes
JO  - Geriatrics
PY  - 1991///
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TI  - Endogenous DNA damage as related to cancer and aging
JO  - Mutat. Res.
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TY  - GEN
AU  - Harman, D.
TI  - Free radical ageing and degenerative diseases
PY  - 1986///
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AU  - Frackowiak, R.S.J.
AU  - Wise, R.J.S.
AU  - Gibbs, J.M.
AU  - Jones, T.
TI  - Positron emission tomographic studies in ageing and cerebrovascular disease at Hammersmith Hospital
JO  - Ann. Neurol.
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AU  - Yamaguchi, T.
AU  - Kanno, I.
AU  - Vermura, K.
TI  - Reduction in regional cerebral metabolic rate of oxygen during human aging
JO  - Stroke
PY  - 1986///
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TI  - Sensitivity of cerebral glucose metabolism, to age, gender, brain volume, brain atrophy and cerebrovascular risk factors
JO  - J. Cereb. Blood Flow Met.
PY  - 1988///
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TI  - Cytochrome oxidase deficiency in Alzheimer's disease
JO  - Annal. N. Y. Acad. Sci.
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TI  - Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported
JO  - JAMA
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AU  - Sokal, R.R.
AU  - Rohlf, F.J.
TI  - Biometry: The principles and pratice of statistics in biological research
PY  - 1969///
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