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Nature Genetics
ISSUE
June 1998, Volume 19 No 2
Editorial
News and Views
Correspondence
Progress
Articles
Letters
About the cover
Editorial Top
Be fruitful and immortalize pp103 - 104
doi:10.1038/446
Full text | PDF (54K)
News and Views Top
Radicals r'aging pp105 - 106
Douglas C. Wallace & Simon Melov
doi:10.1038/448
Full text | PDF (56K)
See also: Letter by Parkes et al.
Mind the GAP, Rho, Rab and GDI pp106 - 108
Stylianos Antonarakis & Linda Van Aelst
doi:10.1038/450
Full text | PDF (97K)
See also: Article by D'Adamo et al.
A chilled-out knockout pp108 - 109
Emiliana Borrelli
doi:10.1038/452
Full text | PDF (67K)
See also: Letter by Timpl et al.
Toxic-waste management in neurons p109
Barbara Cohen
doi:10.1038/454
Full text | PDF (46K)
See also: Article by Cummings et al.
A sugar fix for bone tumours? pp110 - 111
Dominique Stickens & Glen A. Evans
doi:10.1038/458
Full text | PDF (167K)
See also: Letter by McCormick et al.
Touching base p112
doi:10.1038/461
Full text | PDF (68K)
Correspondence Top
HUGO's midlife crisis: life begins at 40 pp113 - 114
Gertjan van Ommen, Bartha Maria Knoppers, Richard Cotton, Joseph Strauss, Sue Povey, Norman Doggett & Luca Cavalli-Sforza
doi:10.1038/464
Full text | PDF (51K)
A putative gene causes variability in lifespan among genotypically identical mice pp114 - 116
Gerald de Haan, Rebecca Gelman, Ada Watson, Edmond Yunis & Gary Van Zant
doi:10.1038/465
Full text | PDF (72K)
Accelerated accumulation of somatic mutations in the senescence-accelerated mouse pp116 - 117
Youichi Odagiri, Hiroyuki Uchida, Masanori Hosokawa, Kazuo Takemoto, Alexander A. Morley & Toshio Takeda
doi:10.1038/468
Full text | PDF (50K)
Mutant myosin VIIa causes defective melanosome distribution in the RPE of shaker-1 mice pp117 - 118
Xinran Liu, Brian Ondek & David S. Williams
doi:10.1038/470
Full text | PDF (148K)
Ile50Val variant of IL4Ralpha upregulates IgE synthesis and associates with atopic asthma pp119 - 120
Hiromichi Mitsuyasu, Kenji Izuhara, Xiao-Quan Mao, Pei-Song Gao, Yojiro Arinobu, Tadao Enomoto, Mitsuru Kawai, Sei Sasaki, Yasuhiro Dake, Naotaka Hamasaki, Taro Shirakawa & Julian M. Hopkin
doi:10.1038/472
Full text | PDF (86K)
Progress Top
Translocations, cancer and the puzzle of specificity pp121 - 124
Frederic G. Barr
doi:10.1038/475
Abstract | Full text | PDF (62K)
Articles Top
Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse pp125 - 133
Mehul T. Dattani, Juan-Pedro Martinez-Barbera, Paul Q. Thomas, Joshua M. Brickman, Raj Gupta, Inga-Lill Mårtensson, Håkan Toresson, Margaret Fox, Jerry K. H. Wales, Peter C. Hindmarsh, Stefan Krauss, Rosa S. P. Beddington & Iain C. A. F. Robinson
doi:10.1038/477
Abstract | Full text | PDF (712K)
Mutations in GDI1 are responsible for X-linked non-specific mental retardation pp134 - 139
Patrizia D'Adamo, Andrea Menegon, Cristiana Lo Nigro, Marina Grasso, Massimo Gulisano, Filippo Tamanini, Thierry Bienvenu, Agi K. Gedeon, Ben Oostra, Shih-Kwang Wu, Anurag Tandon, Flavia Valtorta, William E. Balch, Jamel Chelly & Daniela Toniolo
doi:10.1038/487
Abstract | Full text | PDF (355K)
See also: News and Views by Antonarakis & Van Aelst
The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25 pp140 - 147
Darryl Y. Nishimura, Ruth E. Swiderski, Wallace L. M. Alward, Charles C. Searby, Shivanand R. Patil, Steven R. Bennet, Adam B. Kanis, Julie M. Gastier, Edwin M. Stone & Val C. Sheffield
doi:10.1038/493
Abstract | Full text | PDF (354K)
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1 pp148 - 154
Christopher J. Cummings, Michael A. Mancini, Barbara Antalffy, Donald B. DeFranco, Harry T. Orr & Huda Y. Zoghbi
doi:10.1038/502
Abstract | Full text | PDF (384K)
Letters Top
Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans pp155 - 157
Heiko Krude, Heike Biebermann, Werner Luck, Rüdiger Horn, Georg Brabant & Annette Grüters
doi:10.1038/509
Abstract | Full text | PDF (212K)
The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate pp158 - 161
Craig McCormick, Yves Leduc, Diane Martindale, Kirsten Mattison, Lesley Esford, Angela Dyer & Frank Tufaro
doi:10.1038/514
Abstract | Full text | PDF (212K)
See also: News and Views by Stickens & Evans
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 pp162 - 166
Peter Timpl, Rainer Spanagel, Inge Sillaber, Adelheid Kresse, Johannes M. H. M. Reul, Günter K. Stalla, Veronique Blanquet, Thomas Steckler, Florian Holsboer & Wolfgang Wurst
doi:10.1038/520
Abstract | Full text | PDF (770K)
See also: News and Views by Borrelli
A novel homeobox gene PITX3 is mutated in families with autosomal-dominant cataracts and ASMD pp167 - 170
Elena V. Semina, Robert E. Ferrell, Helen A. Mintz-Hittner, Pierre Bitoun, Wallace Lee M. Alward, Rebecca S. Reiter, Carrie Funkhauser, Sandra Daack-Hirsch & Jeffrey C. Murray
doi:10.1038/527
Abstract | Full text | PDF (354K)
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons pp171 - 174
Tony L. Parkes, Andrew J. Elia, Dale Dickinson, Arthur J. Hilliker, John P. Phillips & Gabrielle L. Boulianne
doi:10.1038/534
Abstract | Full text | PDF (145K)
See also: News and Views by Wallace & Melov
ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins pp175 - 178
Matthew J. F. Waterman, Elena S. Stavridi, Jennifer L. F. Waterman & Thanos D. Halazonetis
doi:10.1038/542
Abstract | Full text | PDF (258K)
Positional cloning of the gene for Nijmegen breakage syndrome pp179 - 181
Shinya Matsuura, Hiroshi Tauchi, Asako Nakamura, Noriko Kondo, Shuichi Sakamoto, Satoru Endo, Dominique Smeets, Brigitte Solder, Bernd H. Belohradsky, Vazken M. Der Kaloustian, Mitsuo Oshimura, Minoru Isomura, Yusuke Nakamura & Kenshi Komatsu
doi:10.1038/549
Abstract | Full text | PDF (321K)
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues pp182 - 186
Kathryn Ann Kolquist, Leif W. Ellisen, Chistopher M. Counter, Matthew M. Meyerson, Lee K. Tan, Robert A. Weinberg, Daniel A. Haber & William L. Gerald
doi:10.1038/554
Abstract | Full text | PDF (1,027K)
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription  pp187 - 191
Peter L. Jones, Gert C. Jan Veenstra, Paul A. Wade, Danielle Vermaak, Stefan U. Kass, Nicoletta Landsberger, John Strouboulis & Alan P. Wolffe
doi:10.1038/561
Abstract | Full text | PDF (290K)
The chromo and SET domains of the Clr4 protein are essential for silencing in fission yeast pp192 - 195
Alla V. Ivanova, Michael J. Bonaduce, Sergey V. Ivanov & Amar J. S. Klar
doi:10.1038/566
Abstract | Full text | PDF (149K)
Genetic mapping of a second myotonic dystrophy locus pp196 - 198
Laura P. W. Ranum, Paul F. Rasmussen, Kellie A. Benzow, Michael D. Koob & John W. Day
doi:10.1038/570
Abstract | Full text | PDF (101K)
Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase pp199 - 202
Hélène LaBranche, Sophie Dupuis, Yaacov Ben-David, Maria-Rosa Bani, Raymund J. Wellinger & Benoit Chabot
doi:10.1038/575
Abstract | Full text | PDF (287K)
Severe growth defect in mouse cells lacking the telomerase RNA component  pp203 - 206
Hiroyuki Niida, Takehisa Matsumoto, Hideo Satoh, Mieko Shiwa, Yoshiki Tokutake, Yasuhiro Furuichi & Yoichi Shinkai
doi:10.1038/580
Abstract | Full text | PDF (266K)
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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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