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Commentary
Nature Genetics  16, 126 - 132 (1997)
doi:10.1038/ng0697-126

A new dimension for the human genome project: towards comprehensive expression maps

Tom Strachan1, 5, Marc Abitbol2, Duncan Davidson3 & Jacques S. Beckmann4, 6

  1Department of Human Genetics, University of Newcastle upon Tyne, UK,

  2Laboratoire d'Embryologie Humaine, Université René Descartes, Paris, France,

  3MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK,

  4Généthon, Evry, France and Fondation Jean Dausset-CEPH, Paris, France.e-mail: tom.strachan@nclac.uk. e-mail:beckmann@genethon.fr

  5e-mail: tom.strachan@nclac.uk

  6e-mail: beckmann@genethon.fr

The current Human Genome Project is largely devoted to structural characterisation of our genome. We now need international co-ordination of a second phase of genome analysis, the systematic construction of expression maps using both basic and high-resolution expression assays. Databases recording different types of expression pattern for a variety of human cell types need to be established and co-ordinated. There is a compelling need for a database of gene expression in early human development, but the scarcity of human material for study requires optimisation of research strategies and co-ordination of expression studies in early human and mouse development.

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EISSN: 1546-1718
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