Focuses and supplements
Nature Genetics provides reviews and commentary illuminating topics of particular interest. In the archive of supplements and focuses you will find in-depth analysis of topics of interest to geneticists.
Top of page
2008
Year of the Rat: Focus on Rat Genetics -
The 'Year of the Rat' offers a mixture of commentaries and primary research papers showcasing the increasing power of rat genetics and its contribution to understanding complex traits. This focus is freely available for three months.
May Vol. 40, Issue 5
Top of page
2007
Question of the Year -
The sequencing of the equivalent of an entire human genome for $1,000 has been announced as a goal for the genetics community, and new technologies suggest that reaching this goal is a matter of when, rather than if. What then? In celebration of its upcoming 15th anniversary, Nature Genetics asked prominent geneticists to weigh in on this question: what would you do if this sequencing capacity were available immediately?
Structural Genome Variation -
We are pleased to announce the publication of a supplement devoted to structural variation in the human genome. This special issue contains comprehensive overviews of each aspect of this burgeoning area in the study of human genetic variation as well as standards and guidelines for future research.
July Vol. 39, Issue 7s
Top of page
2006
microRNAs -
microRNAs are a considerable part of the transcriptional output of the genomes of plants and animals, they regulate a large part of their transcriptomes, and they serve important regulatory functions in widespread biological activities. Thus they must be accounted for if we are to understand the complexity of gene expression and the regulatory potential of the genome. This supplement to Nature Genetics covers the latest advances in the genomic analysis of microRNA function.
June Vol. 38, Issue 6s
Top of page
2005
User's Guide to the Mouse -
A focus examining recent advances in mouse genetics and how to best exploit the vast tools and resources available in the mouse to advance our understanding of significant disease and human health issues.
November Vol. 37, No. 11
The Chipping Forecast III -
The microarray, in all its forms, has been an essential catalyst in promoting a genome-wide view of biology. This supplement to Nature Genetics continues our tradition of covering the latest advances in microarray technology and its applications.
June Vol. 37, Issue 6s
Top of page
2004
Genetics for the human race -
The human genome contains both enough variation for us all to be genetically unique individuals and little enough variation that it is clear we are all members of one human race. The free online supplement of the journal Nature Genetics, "Genetics for the human race", presents a comprehensive survey of what we currently know about the science of human genetic variation. It emerges that the widespread use of "race" as a proxy is inhibiting scientists from doing their job of separating and identifying the real environmental and genetic causes of disease.
September Vol. 36, Issue 11s
Top of page
2003
A User's Guide to the Human Genome II -
Answers to frequently asked questions about how to use genome sequence and annotation, written by leading researchers at the NHGRI to provide an introduction and guide for all genetics and bioinformatics researchers.
September Vol. 35, Issue 1s
A Ten-Year Retrospective -
Reviews drawing on ten years of experience in all the areas that Nature Genetics covers. These reviews provide essential guidance and advice for future research and anticipate the era of pharmacological genomics.
March Vol. 33, Issue 3s
Top of page
2002
The Chipping Forecast II -
These reviews outline the use of microarrays in elucidating genome organization and development, aiding in the diagnosis and prognosis of cancer, and in the selection of drug targets, as well as how to design experiments, weed out noise, analyze data and validate results.
December Vol. 32, Issue 4s
Top of page
1999
The Chipping Forecast -
Many researchers lack a 'nuts-and-bolts' appreciation of the different types of microarray and their manufacture and processing. A detailed and thorough understanding of the options available improves the odds that one's choice will be vindicated; an appreciation of the biological context of genetic (and genomic) questions can also be critical to the success of microarray analysis. The articles in this special supplement of Nature Genetics have been selected with these issues in mind. The limitations and the ultimate utility of the microarray remain to be determined, however, as pointed out in the Foreword by Francis Collins of the National Human Genome Research Institute (NHGRI) — the generous sponsor of this supplement. It is hoped that in addition to serving as a practical resource, the contents of this supplement will provide a glimpse of things to come.
January Vol. 21, Issue 1s