Nature Genetics - Current issue : November 2009 - Vol 41 No 11
Latest highlights
Advance online publication
Genetics of cisplatin ototoxicity
Letter by Colin RossColin Ross and colleagues report the association of variants in TPMT and COMT to cisplatin-induced hearing loss in children. Cisplatin is a widely used chemotherapeutic agent.
Advance online publication
Exome sequencing
Article by Sarah NgMichael Bamshad, Jay Shendure and colleagues report the first application of exome resequencing to a mendelian disorder of unknown cause, Miller syndrome, and identify mutations in DHODH.
Advance online publication
Cucumber genome sequence
Article by Sanwen HuangJun Wang and colleagues report the genome sequence of the cucumber. The cucumber genome is the seventh plant genome sequence to be reported and was assembled with a combination of traditional Sanger and next-generation sequencing methods.
Advance online publication
ETS factors and renal morphogenesis
Article by Benson LuFrank Costantini and colleagues report the identification of the ETS transcription factors, Etv4 and Etv5, as key targets of Ret signaling during kidney branching morphogenesis.
Current issue
Microduplications and schizophrenia
Letter by Shane McCarthyJonathan Sebat and colleagues report the association of microduplication on chromosome 16p11.2 with schizophrenia, whereas the reciprocal microdeletion was associated with autism and developmental disorders.
Advance online publication
Comparative analysis of Mycobacterium leprae
Article by Marc MonotStuart Cole and colleagues report genome sequences and comparative analyses of multiple strains of Mycobacterium leprae, the etiologial agent of leprosy. They define 16 sub-types of M. leprae and examine their geographical distribution.
