Nature Genetics - CURRENT ISSUE : August 2008 - Vol 40 No 8
LATEST HIGHLIGHTS
Advance Online Publication
Pamela Sklar, Nick Craddock and colleagues report a genome-wide association study of bipolar disorder and identify variants in the genes encoding ankyrin G and the alpha 1C subunit of the L-type voltage-gated calcium channel as increasing risk.
Advance online Publication
Masato Kasuga and colleagues and Shiro Maeda and colleagues each report the identification of SNPs in KCNQ1 associated with type 2 diabetes in Japanese, with replications in other East Asian and European populations.
Advance online Publication
Evan Eichler and colleagues present a sequence assembly of the inverted H2 haplotype of human chromosome 17q21.31 and show that the inversion is polymorphic in other great ape species, having occurred independently in the human and chimpanzee lineages.
Advance Online Publication
Andrzej Dlugosz and colleagues report that Hedgehog-dependent skin tumors require canonical Wnt signaling for their development. This suggests a molecular basis for the similarity between early basal cell carcinomas and embryonic hair germs.
CONFERENCE
The Genomics of Common Diseases 2008
ConferenceNature Genetics in association with The Wellcome Trust is pleased to announce the second Genomics of Common Diseases meeting, to be held September 6–9, 2008 at The Broad Institute of MIT and Harvard in Cambridge, MA, USA. The meeting will feature emerging insights into the genetic architecture of complex disorders, and explore the shift toward understanding disease mechanisms and potential applications.
CONFERENCE
Mitochondrial Dysfunction in Neurological Disease
ConferenceIn collaboration with Nature Neuroscience and the Fondation IPSEN, we are pleased to announce a one-day symposium on mitochondrial dysfunction in neurological disease, to be held in Durham, North Carolina on December 5. The meeting aims to bring together geneticists, neuroscientists and cell biologists to highlight recent advances in this field.
