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Translational Research

Basic biomedical research is booming. But its impact, in terms of new therapies and diagnostics, is growing far more modestly. 'Translational research' is seen as a solution to this disparity, ensuring that the bounty of discoveries is effectively 'translated' into benefits in the everyday world of medicine. Nature puts this new discipline in the spotlight, with a special package of features and comment.

Briefing

Podcast

Editorial

  • To thwart disease, apply now

    Translational medicine is a key addition to the biomedical research enterprise. Policy-makers and research leaders now must build the infrastructure to take discoveries from the bench to application.

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Special Report

  • The winding road from ideas to income

    Huge numbers of offices have been established over the past 30 years to help university researchers take their discoveries from the lab to the clinic. Meredith Wadman assesses their success.

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Column

  • A delicate balance

    Near-term and long-term research are vying for attention. David Goldston says that a fuller congressional debate is needed.

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News Features

  • Crossing the valley of death

    A chasm has opened up between biomedical researchers and the patients who need their discoveries. Declan Butler asks how the ground shifted and whether the US National Institutes of Health can bridge the gap.

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  • The full cycle

    Results can be thrust from bench to bedside, but there is also much to be learned by pushing the other way. Heidi Ledford tells tales of clinical trials that have prompted a change in tack.

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  • A case history

    The Ludwig Institute for Cancer Research is focused on translating research into cures. Helen Pearson investigates whether its sometimes unusual methods are producing results.

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Opinion

Book Review

News & Views