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Human Genetics 2009

The flow of human genetic information is growing into a deluge: from high throughput sequencing to genome wide association studies to copy number variation to personal genetic tests. Nature assesses their biological and medical value so far and asks - where should the field go next?

Opinion

  • Genetics without borders

    A UK government scheme to establish nationality through DNA testing is scientifically flawed, ethically dubious and potentially damaging to science.

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  • Putting DNA to the test

    Genetic-testing companies lack regulation, and a list of guiding principles does not go far enough.

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  • An agenda for personalized medicine

    Pauline C. Ng, Sarah S. Murray, Samuel Levy and J. Craig Venter find differences in results from two direct-to-consumer genetics-testing companies. They therefore give nine recommendations to improve predictions.

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  • Let's celebrate human genetic diversity

    Science is finding evidence of genetic diversity among groups of people as well as among individuals. This discovery should be embraced, not feared, say Bruce T. Lahn and Lanny Ebenstein.

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Feature

  • Human genetics: Hit or miss?

    Genome-wide association studies have identified hundreds of genetic clues to disease. Kelly Rae Chi looks at three to see just how on-target the approach seems to be.

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Research

Elsewhere on Nature.com

  • Podcast

    An interview with Pauline Ng on personal genomics and other highlights from the human genetics special.

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