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Published online 5 November 2009 | Nature | doi:10.1038/news.2009.1067

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Brain disease treated by gene therapy

A treatment based on HIV finds first success in humans.

Researchers have halted a fatal brain disease by delivering a therapeutic gene to the stem cells that mature into blood cells.

The gene was transferred using a virus derived from HIV, a technique that researchers have pursued for more than a decade but has not been successful in humans until now.

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