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Published online 14 October 2009 | Nature 461, 862-864 (2009) | doi:10.1038/461862a

News Feature

Neuroscience: Small, furry … and smart

Researchers have engineered more than 30 strains of 'smart mice', revealing possible ways to boost human brains. But, as Jonah Lehrer finds, cognitive enhancement may come at a cost.

Ten years ago, Joe Tsien eased a brown mouse, tail first, into a pool of opaque water. The animal squirmed at first; mice don't generally like getting wet.

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