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Human genetics: Hit or miss?

Genome-wide association studies have identified hundreds of genetic clues to disease. Kelly Rae Chi looks at three to see just how on-target the approach seems to be.

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References

  1. Menzel, S. et al. Nature Genet. 39, 1197-1199 (2007).

    Article  CAS  Google Scholar 

  2. Sedgewick, A. E. et al. Blood Cells Mol. Dis. 41, 255-258 (2008).

    Article  CAS  Google Scholar 

  3. Sankaran, V. G. et al. Science 322, 1839-1842 (2008).

    Article  ADS  CAS  Google Scholar 

  4. Sankaran, V. G. et al. Nature 460, 1093-1097 (2009).

    Article  ADS  CAS  Google Scholar 

  5. O'Donovan, M. C. et al. Nature Genet. 40, 1053-1055 (2008).

    Article  CAS  Google Scholar 

  6. Esslinger, C. et al. Science 324, 605 (2009).

    Article  ADS  CAS  Google Scholar 

  7. Weedon, M. N. et al. Nature Genet. 39, 1245-1250 (2007).

    Article  CAS  Google Scholar 

  8. Sovio, U. et al. PLoS Genet. 5, e1000409 (2009).

    Article  Google Scholar 

  9. Zhou, X., Benson, K. F., Ashar, H. R. & Chada, K. Nature 376, 771-774 (1995).

    Article  ADS  CAS  Google Scholar 

Download references

Authors

Additional information

See Editorial page 697 , and the human genetics online special at http://go.nature.com/VqPUE2 .

Kelly Rae Chi is a freelance writer in Cary, North Carolina.

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Nature Insight: Quantitative Genetics

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A catalogue of published genome-wide association studies by the NHGRI

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Chi, K. Human genetics: Hit or miss?. Nature 461, 712–714 (2009). https://doi.org/10.1038/461712a

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