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Published online 28 May 2009 | Nature | doi:10.1038/news.2009.523

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Flaws found in mouse model of diabetes

Missing protein could limit the use of mice in studies of the disease.

A protein found in humans — but not in mice — could be important for regulating blood sugar and may play a role in diabetes, researchers have found.

The protein, clathrin isoform CHC22, is produced by muscle and fat cells, and is activated by insulin in response to rising levels of glucose in the blood.

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