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Published online 30 March 2009 | Nature | doi:10.1038/news.2009.209

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Experimental design could reduce need for animal tests

Accounting for environmental changes may be better than trying to control them.

Researchers could cut the use of animals in their experiments by changing the way they analyze their results, according to a study by scientists based in Germany and the United States.

In a typical animal experiment, researchers will try to standardize factors such as the animals' genetic backgrounds and laboratory conditions to make it as easy as possible for other researchers to reproduce their results later.

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