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Published online 29 February 2008 | Nature | doi:10.1038/news.2008.634
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HIV's ancient legacy
Lentiviruses may have vexed nonhuman primates for millions of years.
An important antiviral protein, which targets the family of viruses that includes HIV, seems to have evolved twice in nonhuman primates, researchers have found, with one of the versions evolving somewhere between 5 million and 10 million years ago. The results suggest that these viruses played an important role in primate evolution.
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Nowaday,more and more diseases are found.this effect human'live serioully.I think the reason is that humanbeing pay less attention on environment protection.
all can do better ????
Intense persuasion, triggering the innate immune system to initiate the adaptive immune system. A chronic immune response maybe interpreted as weak metabolic signaling. The involved dendrite cells, T cells and macrophages have not been provoked beyond tolerance. Using nicotinic acid to overexpress PPAR will cause unfurling of its' complement genes. This will shift dendrite cells towards MHC release, T-cells, increase TNF and macrophages phagocytotis. Improved functions of PPAR will facilitate the ubiquitin-proteasome system, and other pathways. The enhanced metabolic signals will provoke, usually after six months, the adaptive immune system to differentiate lymphocytes to memory B cell and memory T cells that have complete compliment genes activation. Now under a robust immune response, any chronic infection that has establishes suboptimal activation of dendritic cells, memory B cells and macrophages can be eradicated. SIncerely, Norman A. Smith