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Published online 27 February 2008 | Nature | doi:10.1038/4511042a

Malaria: The end of the beginning

After decades of work, a pioneering malaria vaccine may soon reach the final phase of clinical trials. In the first of two features on efforts against malaria, Brendan Maher reports on a vaccine that is far from perfect - but which may provide new direction and save thousands of lives.

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