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Published online 30 November 2007 | Nature | doi:10.1038/news.2007.219

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A simpler recipe for human stem cells

Adult skin cells turned to pluripotent stem cells without a cancer-causing agent.

Shinya Yamanaka of Kyoto University in Japan has followed the announcement last week of his startling success in turning human skin cells to embryo-like stem cells, by reporting that he has done the same without the cancer-causing agent used in his original recipe.

The work brings scientists perhaps one step closer to the goal of being to use patient-matched stem cells for therapy.

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