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Published online 19 September 2007 | Nature | doi:10.1038/449274a

Biotechs go generic: The same but different

As several lucrative protein-based drugs are poised to go off patent, makers of biopharmaceuticals argue that their products are too complex to be reproduced as generics. Heidi Ledford investigates how close 'biosimilar' drugs can get to the original.

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