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Published online 13 September 2007 | Nature | doi:10.1038/news070910-10
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Gene knockout extends life of mice with ALS
Deleting a single gene almost doubles lifespan.
Knocking out a single gene nearly doubles the lifespan of mice with the animal model of Lou Gehrig's disease, suggesting that the gene may one day become a target for therapies in humans.
Lou Gehrig's disease, otherwise known as amyotrophic lateral sclerosis (ALS), is a neurodegenerative disease that gradually erodes motor control.
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