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Published online 10 September 2007 | Nature | doi:10.1038/news070910-1
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Improved polymer shuttles genes into cells
Biodegradable chemical could one day provide nonviral gene therapy.
Scientists have created a biodegradable polymer that can shuttle DNA into cells, raising the possibility that the compound may one day provide a safer way of performing gene therapy.
There have been more than 1,000 trials of gene therapy, a pioneering way of fixing genetic defects by introducing new genetic material straight into a person's DNA; most of these have been early stages of clinical trials, to test for safety.
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