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Published online 16 May 2007 | Nature | doi:10.1038/news070514-7
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'Guardian gene' may hinder some cancer treatments
But having a mutated p53 gene may help ward off tumours after chemotherapy.
A key gene that helps the body to avoid cancer may sometimes hinder cancer treatment, suggest scientists today. On the flipside, the mutated version of the gene, which usually cannot protect against cancer, might work to a patient's advantage during therapy.
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