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Published online 25 January 2007 | Nature | doi:10.1038/news070122-10

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Fresh light thrown on tragic drug trial

Animal tests may have missed danger because monkeys 'too clean'.

Immunologists have a new theory to explain why the devastating effects of the experimental drug TGN1412 were not spotted in animal tests. The 'superantibody' drug put six volunteers in intensive care in a London hospital last March.

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