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Published online 6 December 2006 | Nature | doi:10.1038/news061204-8
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Why did a promising heart drug fail?
Doomed drug highlights complications of meddling with cholesterol.
The failure of a high-profile cholesterol drug has thrown a spotlight on the complicated machinery that regulates cholesterol levels. But many researchers remain confident that drugs to boost levels of 'good' cholesterol are still one of the most promising means to combat spiralling heart disease.
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