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Published online 22 June 2006 | Nature | doi:10.1038/news060619-11
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Brain 'traffic jams' drive Parkinson's symptoms
Stopping cellular tailbacks could speed the way to therapies.
Using a zoo of animals from yeast to rats, US scientists have shown that speeding the flow of proteins in cells might relieve one of the underlying causes of Parkinson's disease.
During the disease, brain neurons that make the chemical dopamine wither and die, causing the movement problems that characterize Parkinson's.
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