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Published online 21 April 2006 | Nature | doi:10.1038/news060417-8

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Chronic fatigue has genetic roots

Massive data-crunch points to basis of inscrutable disease.

The largest study yet of chronic-fatigue syndrome (CFS) has revealed a battery of genetic changes that might explain how the mystery disease arises.

The condition, sometimes called myalgic encephalomyelitis (ME), causes exhaustion and problems with sleep and memory.

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