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Published online 7 March 2006 | Nature | doi:10.1038/news060306-9

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Coffee mixes badly with certain genes

Caffeine boosts risk of heart attacks in the genetically susceptible.

People carrying a common variation in a certain gene could be worsening their risk of a heart attack simply by drinking several cups of coffee per day.

A possible link between coffee and heart disease has been tested before, but the results have been controversial.

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