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Published online 7 September 2005 | Nature | doi:10.1038/news050905-9

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Smaller prion clusters are catching

Caution advised in treatment of brain disease.

When it comes to deadly protein clusters in the brain, size matters.

The human equivalent of mad cow disease, variant Creutzfeldt-Jakob disease (vCJD) is thought to be caused by misshapen proteins, known as prions, that infect the brain.

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