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Published online 25 August 2005 | Nature | doi:10.1038/news050822-6

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Surging hormones blamed for pain

Study of sex-change patients reveals role of oestrogen.

Women have long been known to experience more pain than men. And the idea that sex hormones are to blame has just been bolstered by a study into pain thresholds in a unique study group: people undergoing sex-change operations.

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