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Published online 21 October 2004 | Nature | doi:10.1038/news041018-14
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Key genes may not create Down syndrome
Mice model suggests cause is more complex than thought.
The small group of genes long believed to cause Down syndrome are unlikely to be the real culprits, according to recent research in mice. The finding is bad news for those devising therapeutic strategies, whose job would be simplified if blame could be laid at the door of just a few genes.
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