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Published online 20 December 2002 | Nature | doi:10.1038/news021216-14

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Ultrasound scan spots Down's syndrome

Nasal bone holds key to safer test for birth defects.

An ultrasound scan could save many mothers the decision over whether to have an amniocentesis and risk losing a baby.

Nearly two-thirds of 15-22-week-old fetuses with Down's syndrome lack a nasal bone, fetal-medicine specialist Kypros Nicolaides, of King's College, London, and his colleagues found1.

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