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Eyes left

A gene called Pitx2 that tells left from right is more subtle than first imagined. For a start, there are at least two forms of the gene, each with its own functions.

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References

  1. Ryan,A.K., Blumberg, B. & Belmonte, J.C. I. Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature 394, 545 - 551; 1998.

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  2. Essner,J.J., Branford, W.W., Zhang, J. & Yost, H.J. Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms. Development 127, 1081 - 1093 2000.

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Gee, H. Eyes left. Nature (2000). https://doi.org/10.1038/news000217-6

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  • DOI: https://doi.org/10.1038/news000217-6

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