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Published online 6 March 2003 | Nature | doi:10.1038/news030303-7

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Monoclonal antibodies inhibit prion replication and delay the development of prion disease

Therapy looks best yet to tackle brain disease.

The possibility of using antibodies to treat variant Creutzfeldt-Jakob disease (vCJD) receives a boost this week, with the first promising results from an animal trial.

The lethal brain condition - which is a human version of mad cow disease - occurs when healthy proteins called prions become twisted and clump together.

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