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Published online 21 February 2003 | Nature | doi:10.1038/news030217-12
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Transgenic mosquitoes unfit for duty
Malaria-resistant insects must be bred for success
Mosquitoes genetically engineered to be immune to malaria - a hope for ridding the world of the disease - won't get off the ground without serious help, new research warns1.
Cloned from a single ancestral insect and reared in the laboratory for years, transgenic mosquitoes are so inbred that they can't cut it in the wild, find Andrea Crisanti and colleagues at Imperial College in London.
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