Molecular keys that lock enzymes out of harm's way can be moulded within the enzymes themselves.
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References
Nguyen,R.& Huc, I. Using an enzyme's active site to template inhibitors. Angewandte Chemie International Edition 40,1774-1776(2001).
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Ball, P. Drugs fill a gap. Nature (2001). https://doi.org/10.1038/news010524-10
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DOI: https://doi.org/10.1038/news010524-10