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Published online 23 March 2001 | Nature | doi:10.1038/news010329-4

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Missing gene emasculates mice

We're one step closer to understanding how some animals develop into males and others females.

Researchers have discovered a gene without which male mice develop as females1.

This new genetic player in sex determination may help us to explain some of the cases where humans with a Y chromosome -- who should develop as males -- show some degree of female sexual anatomy.

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