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Article
Nature Neuroscience - 9, 1134 - 1141 (2006)
Published online: 13 August 2006; | doi:10.1038/nn1749

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

Catherine Heurteaux, Guillaume Lucas, Nicolas Guy, Malika El Yacoubi, Susanne Thümmler, Xiao-Dong Peng, Florence Noble, Nicolas Blondeau, Catherine Widmann, Marc Borsotto, Gabriella Gobbi, Jean-Marie Vaugeois, Guy Debonnel & Michel Lazdunski

Supplementary Fig. 1 (pdf 1M)
TREK-1 immunolocalization throughout the network of limbic, striatal and prefrontal cortical neuronal circuits.

Supplementary Fig. 2 (pdf 640K)
TRAAK expression in 5-HT neurons of the dorsal raphe nucleus.

Supplementary Fig. 3 (pdf 284K)
5-HT selective reuptake inhibitors (SSRIs) inhibit human TREK-1 but not TRAAK currents.

Supplementary Fig. 4 (pdf 32K)
Mean whole-brain fluoxetine concentrations after acute and chronic fluoxetine treatment.

Supplementary Note (pdf 160K)


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Nature Neuroscience
ISSN: 1097-6256
EISSN: 1546-1726
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