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Brief Communication
Nature Neuroscience 9, 999–1000 (1 August 2006) | doi:10.1038/nn1735
Specification of auditory sensitivity by Drosophila TRP channels
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Abstract
Ears achieve their exquisite sensitivity by means of mechanical feedback: motile mechanosensory cells through their active motion boost the mechanical input from the ear. Examination of the auditory mechanics in Drosophila melanogaster mutants shows that the transient receptor potential (TRP) channel NompC is required to promote this feedback, whereas the TRP vanilloid (TRPV) channels Nan and Iav serve to control the feedback gain.
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