Seeking a function for spontaneous neurotransmission
ChiHye Chung &
Ege T Kavalali
The authors are at the Center for Basic Neuroscience and the Department of Physiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9111, USA. ege.kavalali@utsouthwestern.edu
A recent study proposes that the random and spontaneous, NMDA receptor–dependent miniature postsynaptic currents at hippocampal synapses serve to regulate local postsynaptic protein synthesis, thereby stabilizing synaptic function.
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