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Brief Communication
Nature Neuroscience 9, 868–869 (1 July 2006) | doi:10.1038/nn1713
Cocaine self-administration selectively abolishes LTD in the core of the nucleus accumbens
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Abstract
The core and shell of the nucleus accumbens have critical, differential roles in drug-dependent behaviors. Here we show that operant cocaine self-administration inhibits long-term depression (LTD) in both structures after 1 d of abstinence.
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