The anterior cingulate cortex (ACC) is thought to detect unfavorable outcomes and thus influence behavior. A new paper reports that ACC-lesioned monkeys respond normally to reduced rewards, but do not maintain their improved behavioral strategy. The ACC thus is not a simple error detector, but an integrator of past reward experience.
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Hayden, B., Platt, M. Fool me once, shame on me—fool me twice, blame the ACC. Nat Neurosci 9, 857–859 (2006). https://doi.org/10.1038/nn0706-857
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DOI: https://doi.org/10.1038/nn0706-857
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