Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
Brief Communication
Nature Neuroscience 9, 602–604 (1 May 2006) | doi:10.1038/nn1678
Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation
&
Abstract
Postnatal glutamatergic principal neuron synapses are typically presumed to express only calcium-impermeable (CI), GluR2-containing AMPARs under physiological conditions. Here, however, we demonstrate that long-term potentiation (LTP) in CA1 hippocampal pyramidal neurons causes rapid incorporation of GluR2-lacking calcium-permeable (CP)-AMPARs: CP-AMPARs are present transiently, being replaced by GluR2-containing AMPARs |[sim]|25 min after LTP induction.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
